Developing and Validating the Multimodal Therapeutic Coherence Index (MTCI): A Standardized Tool to Predict Patient Outcomes Across Medical Specialties
DOI:
https://doi.org/10.47352/jmans.2774-3047.233Keywords:
Multimodal Therapeutic Coherence, Patient Outcome Prediction, Medical Specialties, Standardized Index, Clinical Decision Support, Therapeutic Integration, Personalized Medicine, Predictive AnalyticsAbstract
Multimodal therapeutic approaches are essential for managing complex diseases, yet tools to assess the coherence of combined treatments remain lacking. This study introduces the Multimodal Therapeutic Coherence Index (MTCI), a standardized tool designed to quantify the alignment and synergy of therapies across medical specialties. Developed through expert consensus and validated in over 6,000 patients, the MTCI demonstrated strong predictive power for clinical outcomes such as mortality, readmissions, and quality of life. Case studies in oncology, cardiology, and rehabilitation illustrate its practical use. The MTCI offers a valuable decision support tool to optimize integrated care and personalize treatment strategies, with potential for embedding in health IT systems to support real-time clinical management. [1]
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Abdulmalik Alanazi, Manal Eid Afana Alshrari, Shatha Sadan Alrashedi , Khalid Saleh Saad Albalawi, Najat Sulaiman Albalwi , Hanan Mulebis Alanazi, Yazeed Alzahrani, Omar Maqbul Mutaq, Norah Rebh Onayzan Albaqami, Abeer Abdalaziz Alhatim (Author)

This work is licensed under a Creative Commons Attribution 4.0 International License.
- Authors retain copyright and acknowledge that the Journal of Multidisciplinary Applied Natural Science is the first publisher, licensed under a Creative Commons Attribution 4.0 International License.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges and earlier and greater citation of published work.





