Advances in Diagnostic Approaches for Respiratory Infections

Abstract

Respiratory infections remain a leading cause of morbidity and mortality worldwide, challenging clinicians and public health systems to improve early and accurate diagnosis. Recent advances in molecular diagnostics, metagenomic sequencing, biosensor technology, and digital health platforms offer transformative potential for respiratory infection detection and management. This article reviews the current state of respiratory infection diagnostics, highlighting key technological innovations, clinical case studies, and ongoing challenges. By integrating next-generation sequencing, rapid point-of-care molecular assays, and novel breath-based tests, healthcare providers can better tailor treatments, reduce antibiotic misuse, and enhance outbreak surveillance. The continued development and deployment of these diagnostic tools are essential to combating both endemic and emerging respiratory pathogens in a post-pandemic world.